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Международная инженерная академия, Инженерная академия Грузии,

Редакция  журнала `Georgian Engineering News~,

Грузинский технический университет

 

 

ПОЗДРАВЛЯЮТ БОРИСА ВЛАДИМИРОВИЧА ГУСЕВА

с 80-летием со дня рождения

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Б.В. ГУСЕВ

 

 

Известному ученому, педагогу, государственному и общественному деятелю, профессору, академику Борису  Владимеричу Гусеву  исполнилось 80 лет.

Б.В. Гусев один из основателей и первый президент Инженерной академии СССР (1990 г.), преобразованной впоследствии в Российскую и Международную инженерные академии (1991 г.), президентом которых он является со дня их основания, президент Российского Союза общественных академий наук.

Б.В. Гусев родился 13 мая 1936 года. Окончил Тырновскую семилетнюю школу, Рязанский техникум (ныне колледж) железнодорожного транспорта. После окончания двух курсов Московского института инженеров железно­до­рож­ного транспорта направлен в Варшавский политехнический институт, который окончил в1961 г.

Трудовую деятельность начал в 1961 году в Ташкентском институте инженеров железнодорожного транспорта, с 1964 по 1973 год работал в Днепропетровском институте инженеров железнодорожного транспорта. С 1973 по 1979 год являлся заместителем директора конструкторско-технологического бюро «Мосоргстройматериалы». В 1978 году присвоена учёная степень доктора технических наук. С 1979 по 1990 год последовательно занимал посты заведующего лабораторией и заместителя директора Научно-исследо­вательского института бетона и железобетона НИИЖБ. В 1981 году присвоено учёное звание профессора. С 1990 года по настоящее время - президент Российской инженерной академии. С 1991 года - член-корреспондент РАН. С 2004 года - иностранный член Черногорской академии наук и искусств.

Б.В. Гусев широко использует математические методы при изучении проблем долговечности и коррозионных процессов. Им разработаны основы построения развитых физико-химических и математических моделей и выполнена их структурная идентификация.

В настоящее время Б.В. Гусев занимается разработкой основы наноструктурирования цементных систем для повышения прочности бетона (в 2-3 раза) и создания суспензий и эмульсий высокой однородности и нерасслаиваемости при получении различных материалов, в том числе для создания защитных наноплёнок.

Широкомасштабная научная и просветительская деятельность Б.В. Гусева известна во многих странах. Он является автором более 500 научных публикаций, 25 монографий и учебных пособий, 150 изобретений и патентов. Б.В. Гусев является основателем научной школы, под его руководством подготовлено 85 докторов и кандидатов наук во многих странах мира. Гусев Б.В. ведет широкомасштабную и активную работу по развитию международных научно-технических связей как организатор многих научно-технических конгрессов, конференций, симпозиумов и выставок.

За активную деятельность по развитию международного научно-технического сотрудничества в 1998 г. Международной энциклопедической организацией (г. Лондон) Гусев Б.В. признан «Человеком года», в том же году награждён орденом Послов (г. Нью-Йорк).

Большая общественная деятельность Гусева Б.В. проявилась в работе научно-технических советов Российской академии наук, в Экспертных советах при Правительстве РФ и Высшей аттестационной комиссии Минобразования РФ, руководителя диссертационных Советов и члена научно-технических Советов ряда министерств и ведомств России.

Борис Владимирович Гусев награжден: золотым знаком Союза польских студентов, Золотой медалью Белорусской, Украинской, Грузинской, Казахской инженерных академий и другими медалями и почетными званиями стран мира, Лауреат Государственной премии СССР, имеет медаль «За трудовое отличие». Является Почетным доктором Грузинского технического университета,  Почетным членом инженерных академии Грузии, Казахстана, Украины, Белоруссии, действительным членом Академии творчества.

 

 

 

 

 

 

 

SUMMARY

RUSSIAN ACADEMY OF ENGINEERING – A POWERFUL ENGINE OF INTEGRATION OF THE ENGINEERING COMMUNITY

Gusev B.V.

International Engineering Academy

The Russian Academy of Engineering is the successor of the Engineering Academy of the USSR established on the 13th of May, 1990. From the very beginning, the Engineering Academy launched targeted efforts to strengthen the links between science and industry, to resolve the problems associated with the application of the results of fundamental research and their accelerated adaptation to industry. The Engineering Academy contributed and contributes to the preservation and development of the intellectual potential of science and engineering by effective implementation of the fundamental achievements of science in the industrial sector. 

Keywords: Russian Academy of Engineering, engineering activity, fundamental research, new technology.

 

 

 

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Международная инженерная академия, Инженерная академия Грузии,

Редакция  журнала `Georgian Engineering News~,

Грузинский технический университет

 

 

 

ПОЗДРАВЛЯЮТ АРЧИЛА ИВЕРИЕВИЧА ПРАНГИШВИЛИ

с  избранием Вице-президентом Международной инженерной академии

А. И. ПРАНГИШВИЛИ 

 

 

 Арчил Ивериевич  Прангишвили  -  ректор Грузинского технического университета, президент Грузинской инженерной академии, вице-президент Международной инженерной академии, доктор технических наук (1992), профессор (1995), академик Национальной академии наук Грузии (2013) и других международных и зарубежных академий.

А. И.  Прангишвили  родился 13 апреля 1961 года в гор. Тбилиси. В 1983 г. окончил факультет автоматики и вычислительной техники Грузинского политехнического института  по специальности «инженер-системотехник». В тот же год  он поступил в аспирантуру кафедры вычислительной техники Грузинского политехнического института, а в 1987 г. защитил диссертацию на соискание учёной степени кандидата технических наук в Московской инженерно-физическом институте.  После защиты кандидатской диссертации 1987-1988 гг. – старший научный сотрудник Проблемной лаборатории Грузинского технического университета, доцент кафедры вычислительной техники Грузинского технического университета.

В 1992 г. защитил докторскую диссертацию по техническим наукам.  В1992-2003 гг. – заместитель директора Института информатики, систем управления и телекоммуникаций Грузинского технического университета, 1992-2005 гг. – научный руководитель Научно-исследовательской лаборатории компьютерных и информационных технологий Грузинского технического университета, 2002-2005 гг. – чрезвычайный уполномоченный президента Грузии в сфере энергетики, с 2009 г по сегодняшний день – ректор Грузинского технического университета.

С 2013 г. – Член Управляющего совета Международного благотворительного фонда возрождения и развития духовности, культуры и науки  Католикоса-Патриарха Всея Грузии,

С 2011 г. по сегодняшний день – представитель Грузии в финансовом комитете Международной организации «Центр ядерных исследований» (г. Дубна, Российская Федерация),

С 2011 г. – представитель Грузии в Совете по развитию нанотехнологий в странах ГУАМ-а с 2010 г. – руководитель группы по изучению проблем нанотехнологии Национальной академии наук Грузии.

 Награждён орденом Чести.  А. И. Прангишвили  дважды (1990г и 2012г) присвоена Национальная премия Грузии.

Под его научным руководством защищено 20 кандидатских и докторских диссертаций.

Является автором более 200 научных работ, в том числе 20 монографий, 11 учебников и 20 патентов.

 

 

 

SUMMARY

GEORGIAN ENGINEERING ACADEMY: FUNDAMENTAL PRINCIPLES OF ORGANIZATION MANAGEMENT IN RESPECT OF SYSTEM LAWS 

Prangishvili A.I.

President of the Georgian Engineering Academy

The scientific activity is the system activation associated with scientific research including  fundamental studies with revealing the laws and mechanisms of processes and phenomena, and applied ones studying the possibilities for deriving practical benefit from the knowledge gained. The scientific and technical activities of the Georgian Engineering Academy represent the synergy of scientific, engineering and organizational activities, which, in its turn, implies research, R&D and technological work, including scientific studies and technological developments ending by production and testing of prototypes.

Keywords: Georgian Engineering Academy, engineering activity, fundamental research, new technology.

 

 

 

SUMMARY

STRUCTURING AND «WEIGHING» OF THE GOALS IN THE TASK OF SUSTAINABLE DEVELOPMENT OF THE REGION

Prangishvili A.I., Namicheishvili N.O., Gasitashvili Z.A., Verulava D.Y. and Kiknadze M.G.

Georgian Technical University

A significant step in the establishment, development and realization of the organizational system is a pre-design analysis and modeling. The development of modern, large-scale and complex systems revived interest in the techniques of their modeling, including the development and analysis of the system model. We can formulate a set of goals and factors based on the analysis of complex organizational systems. Usually, these goals are structured, i.e. consist of sub-goals, these sub-goals may include other sub-goals, etc. As a result, we get a list of atomic goals. The number of sub-goals may be very large. Also we must underline that particular elements of these atomic goals do not have an equal impact on the  main goal. The selection of an optimal set of system goals and information technology for system operation includes several stages. The objective of the paper is to develop the theory and methodology of economic-mathematical modeling based on a cognitive approach to the research methodology and decision-making for sustainable development of regional socio-economic systems. The present study considers the possibility of applying the cognitive analysis to the solution of the following tasks: minimization of the local goals based on the  mathematical model; selection of more important goals among the obtained local goals; expert estimation of goals interrelation  and establishment  of   goals weights for the developed model; minimization of the local goals based on the mathematical model; construction of the model of the region sustainable development based on the cognitive modeling methodology.

Keywords: local goals, weights of goals, expert estimation, tree of goal, structurization of system goals, indicators of sustainable development.

 

 

 

 

SUMMARY

DISTORSION COMPENSATION IN SIMPLE REPRODUCING SYSTEMS

Morozov V. P. and Babayan R.R.

V. Trapeznikov Institute of Control Sciences of  RAS, Moscow, Russia

The circuit of the analog scaling unit with additional amplifier circuitry for distortions extraction and compensation is presented.

Keywords: reproducing system, analog scaler, amplification error, compensation.

 

 

SUMMARY

INTELLIGENT CONTROL MECHANISMS

Burkov V.N., Burkova I.V., Gasitashvili Z.A., Gorgidze I.A., Javakhadze G.S. and Khutsishvili S.A.

V. Trapeznikov Institute of Control Sciences of RAS, Moscow, Russia

Georgian Technical University

The paper deals with intelligent control mechanisms. Some examples are given. The elaboration of intelligent control mechanisms is based on the active systems theory. For further  progress of economy the state program “Intelligent Control” is essential.

Keywords:  intelligent control, active systems.

 

ROBUST DECENTRALIZED INVENTORY CONTROL IN LARGE-SCALE SUPPLY NETWORKS

 

Lyubchyk L. M. and Dorofieiev Yu.I.

 

National Technical University “Kharkiv Polytechnic Institute”

 

Abstract.The problem of decentralized inventory control in large-scale supply chains under uncertain but bounded external demand and transport time-delays and in the  presence of asymmetric structural constraints on states and controls is considered. Local inventory controllersuse linear dynamic feedback with respect to deviation of the current inventory levels from the chosen safety levels. To suppress the influence of disturbances, modelling external demand, while ensuring robust stability of closed local subsystems, the method of invariant ellipsoids is used, which allowed formulating the problem in terms of linear matrix inequalities, wherein the synthesis of control reduced to a semi-definite programming problem. Stability analysis of inventory control systems for large-scale supply networks with decentralized controllers is performed using the comparison method and vector Lyapunov functions technique.

Keywords: invariant ellipsoids, inventory control, linear matrix inequality, semidefinite programming, comparison method, robust control, supply network, vector Lyapunov function.

 

 

 

 

ABSOLUTE CONVERGENCE AND SUMMABILITY OF THE FOURIER-BESSEL SERIES

 

Skhirtladze I.A. and Skhirtladze N.I.

 

V. Chavchanidze Institute of Cybernetics, Georgian Technical University

 

Abstract. The sufficient conditions for absolute convergence and summability of the Fourier-Bessel series are given.

Keywords: Fourier-Bessel series, absolute convergence, absolute summability.

 

 

SUMMARY

NUMERICAL SIMULATION OF LITHODYNAMICS PROCESSES IN THE AREA OF THE CHANNEL TO THE PORT OF POTI: ENGINEERING MEASURES AGAINST SILTING CHANNEL

Saghinadze I.S., Bregvadze A.V. and  Gagoshidze Sh.N.

Akaki Tsereteli State University, Kutaisi

Georgian Technical University

In the paper the problem of protecting the channel and internal waters of the Poti port from silting is discussed. A mathematical model of  lithodynamics of the channel and  the algorithm for the numerical solution of the  problem are designed. The finite element method and the Crank-Nicholson scheme are used. The numerical experiments show that the deposition of sediment in the channel is intense 0.7-0.8m/year. Engineering measures are proposed to solve the existing problems.

Keywords:  seaport channel, silting,  lithodynamics, numerical simulation, engineering measures.

 

TRANSVERSE DAMPING OF MAIN PIPELINES OF HYDROTRANSPORT SYSTEMS UNDER THE INFLUENCE OF PARAMETRIC FORCES

 

Makharadze L.I. and Gavasheli L. Sh.

 

Georgian Technical University

 

Abstract: The paper deals with damping of transverse vibrations in main hydrotransport pipelines with consideration for the effect of parametric forces. It was determined that the transverse (parametric) forces are damped when an flexible dampimg device is installed at one end of the pipeline. The intensity of transverse vibrations increases with the damping factor and the liquid mass (hydro-air mixture) flow velocity in the pipeline. Besides, the system is entirely in the low-frequency range of transverse vibrations, which, for its part, exerts an additional effect on the sustainability and reliability, i.e. the safe operation, of the main.

Keywords: hydrotransport systems, main pipeline, liquid mass, flow frequency, vibration, flexible damping device.

 

SUMMARY

WEB DESIGN COLOR THEORY

Namchevadze  Ts.V.

Akaki Tsereteli State University, Kutaisi

The paper deals with the color theory for web designers. It considers the factors determining the color harmony: color complementation and contrast according to color, brightness, and saturation. Some combinations of achromatic and chromatic colors are considered. There are established the types of color harmony: monochromatic, analogous, complementary, analogous-complementary, split-complementary, triad and rectangle.

Keywords: color theory, web design, color harmony.

 

SUMMARY

WEB DESIGN FOR MOBILE DEVICES

Namchevadze  Ts.V.

Akaki Tsereteli State University, Kutaisi

The paper deals with web design for mobile devices. It is emphasized that, to make a web design for such devices, it is essential to know the display capability in pixels. For this purpose, a mobile version of design is necessary. With this in mind, desired applications and functions must be installed. There are such utility software that facilitate the work of a web designer.

Keywords: web design, mobile device, Apple iPhone, service, utility.

 

 

SUMMARY

THERMOSYPHON COOLING SYSTEM FOR SOLAR THERMOELECTRIC TRANSDUCERS

Khachidze T.I. and Avaliani I.M.

LEPL Institute “Optica”

Georgian Technical University

The paper deals with the design of a  thermosyphon cooling system for solar cells. From the obtained investigation results, it can be inferred that the thermosyphon system is efficient for cooling the thermoelectric transducers with high concentration of solar energy. At the same time, this system provides high  temperature stability of the cells.

Keywords: solar cell, thermoelectric transducer, thermosyphon cooling system.

 

SUMMARY

GEORGIA’S ROLE AS A EURASIA’S TRANSPORT CORRIDOR

Margalitadze I.N., Gegeshidze E.I. and Gabidzashvili L.G.

Georgian Technical University

Georgia should participate in international transport programs to realize fully Georgia's geopolitical potential and to integrate in the international transport system. By participating in the TRACECA (Transport Corridor Europe-Caucasus-Asia) program, Georgia is involved in the sphere of interests of global powers. In the framework of TRACECA, Georgia becomes a strategic partner of the European Union.

Keywords: TRACECA, transport corridor, transit, geopolitics

 

SUMMARY

RESEARCH OF THE PROPERTIES OF EXPLOSIVES PRODUCED ON THE BASIS OF UTILIZED AMMUNITION

Khomeriki S.K., Kuchukhidze Z.K., Apriashvili A.G., Shatberashvili G.G., Abesadze N.A.

and  Aptsiauri A.M.

G. Tsulukidze Mining Institute

The problems of storage or mass destruction of ammunition expired are put forward. Recycling of out-of-date ammunitionopens ample opportunities of use of fighting equipment in the industry. At G. Tsulukidze Mining Institute, in the project framework, based on utilized ballistite and pyroxylin gunpowder, cheap and highly effective industrial safe explosives were developed, which application at open mining operations, besides considerable economic benefit, provides a higher level of ecological safety of recycling in comparison with their

destruction on open ranges. At the Laboratory of Explosives Research and Blasting Technologies of                  G. Tsulukidze Mining Institute, the gravitation density and the speed of charge detonation were experimentally defined.  As is obvious from the presented data, the experimental structures based conversion explosive compounds by their detonation characteristics surpass the explosives (ANFO).

Keywords: recycling, utilized ammunition, explosives, ballistite, pyroxylin gunpowder, conversion, open charge, intermediate detonator, speed of detonation, critical diameter.

 

OPTICAL CONTROL OF THE TRANSMISSION SPECTRUM OF THE OPTICALLY ACTIVE LIQUID CRYSTAL LAYER

 

Ponjavidze N.T., Bortolozzo U., Residori S., Chanishvili A.G., Chilaya G.S. and     Petriashvili G.Sh.

 

Nonlinear Institute of Nice, France

Institute of Cybernetics of Georgian Technical University

 

Abstract. A several micron thick layer of a photosensitive optically active liquid crystal material possessing the optical activity of a very high value was studied. A photoinduced change in optical rotation resulting in a significant shift of the transmittance spectrum of the layer between crossed polarizers was obtained.

Keywords: optical activity, cholesteric liquid crystal, photosensitivity, optical information recording.

 

SUMMARY

CRYSTAL STRUCTURE OF [Mg(OH2)6](NH4)2(SO4)2

Zazashvili S. R., Beridze L.A. and  Miminoshvili K.E.

Georgian Technical University

Tbilisi State Medical University

There was studied the structure of compound [Mg(OH2)6](NH4)2(SO4)2 (a = 6,7426(5); b = 16,053(1);                        c = 23,095(2) Å; β  = 97,787(2)º; T = 153K, P21/n, Z = 2, R(F) = 0,0267,). The compound is formed of cations: [Mg(OH2)6]2+, two - (NH)+ and two anions (SO4)2-.

Ключевые слова: X-ray structure analysis, complex compounds, magnesium, sulphate, ammo­nium. 

 

 

DETERMINATION OF THE SHARE OF THE ELECTRIC QUADRUPLE ADMIXTURE FOR THE 169Tm 93.61 keV g–TRANSITION

 

Metskhvarishvili M.R., Razmadze T.O., Kvirikashvili M.G., Baramidze K.K.,  

Beridze M.G. and Shogiradze M.Kh.

 

Georgian Technical University

 

Abstract. The results of investigation of the internal conversion electron spectrum of the169Tm 93.61 keV                  g-transition are presented. A magnetic prism beta spectrometer with 0.04% resolution was used for the measurements. The forms of   conversion lines were studied, and the values of their expansion ratio were determined. From the determined internal conversion coefficients, the mean value of d2 was calculated, d2=0.034±0.003. The average value of the share of the electric quadruple admixture equal to a=(3.3±0.3)% was found, which corresponds to the M1+3.3%E2 mixed g-transition.

Keywords: g-transition, internal conversion coefficients, multipole.

 

SUMMARY

HEAT-RESISTANT COMPOSITION BASED ON POLYNAPHTOYLEN BENZIMIDAZOLE

Ormotsadze N.Sh., Meskhishvili M.M. and Bibileishvili D.V.

Akaki Tsereteli State University, Kutaisi

Georgian Technical University

The objective of the research involves the reduction of layer defectiveness, veil removal at etching of the polymer lacquer and an increase of its stability at storage. The aim is attained by using the composition based on the different-section structure containing o-aminophenyl-naphtoylimide and naphtoylen benzimidazole fragments with the blocked - end anhydryde groups.The method for preparation of press-materials based on polynaphtoylbenzimidazole by means of thermal polycyclocondensation was developed.

Keywords: heat-resistant composition, polynaphtoylen benzimidazol, polycyclocondensation.

 

SUMMARY

THE IMPACT OF SOME PARAMETERS ON THE SORPTION PROPERTIES OF NATURAL GEORGIAN ZEOLITES

Gudushauri  Ts.N., Kochiashvili M.S. and Ugrekhelidze I.R.

Georgian Technical University

The correlation between the zeolites studied and some parameters was made based on the experimental results. As a function is taken the correlation of exchange capacity with the parameters such as the content of zeolite in a mineral, the kinetic (effective) diameter of windows and the Si:Al ratio. The determined correlation can be used as a justified zeolite criterion for separation of rare and intermediate metals, and for development of new chromatographic concentration methods.

Keywords: zeolite, sorption, sorbent, DOE.

 

SUMMARY

MICRO-COLUMN LIQUID CHROMATOGRAPHY OF SUNFLOWER OIL PHOSPHOLIPIDS 

Siradze M.G.,  Berdzenishvili I.G.,  Neparidze N.S., Jokhadze G.A., Tvaliashvili V.B. and  Diogidze O.Sh.

Georgian Technical University

Batumi State Maritime Academy

The developed technique is suitable for the analysis of  concentrates of  phospholipids if their content in the concentrate is no less than 50%. If the share of neutral lipids is above 50%, it is expedient to separate the  phospholipid concentrate from neutral lipids. Special requirements are imposed on  the purity of solvents meant for the mobile phase. Acetonitrile and methanol should be of  the `superpure for HPLC” grade, i.e. they must not have intense absorption at the wavelength above 200 nm.

Keywords: phospholipids, sunflower oil, micro-column HPLC.

 

Summary

Mathematic-chemical Investigation of Acetylene TRimerization and CycloTRimerization Reactions 

Lobdjanidze T.E., Gverdtsiteli M.I. and Giorgadze K.P.

Iv. Javakhishvili Tbilisi State University

Within the scope of the quasi-ANB-matrices method, the mathematic-chemical investigation of acetylene trimerization and cyclotrimerization reactions was carried out. These reactions proceed with the decrease of molecular complexity.

Keywords: trimerization, cyclotrimerization, quasi-ANB-matrices method.

 

SUMMARY

ALGEBRAIC CHARACTERISTICS OF PLATO’S BODIES AND THEIR APPLICATION IN MODELING OF COORDINATION COMPOUNDS

Rusia M.Sh., Lobjanidze L.B. and  Gverdtsiteli M.I.

Iv. Javakhishvili Tbilisi State University

Algebraic characteristics of Plato’s bodies were elaborated within the scope of the matrices method. The concept of pseudo-contiguity and modified pseudo-contiguity matrices was introduced. The application of this approach to modeling of coordination compounds is considered.

Keywords: Plato’s bodies, graph, modified pseudo-contiguity matrix, coordination compounds.

 

MATHEMATICAL-CHEMICAL INVESTIGATION OF ALKENES

 

Kvartskhava G.R., Chachava G.G. and  Gverdsiteli M.I.

 

Georgian Technical University

National Food Agency

Iv. Javakhishvili Tbilisi State University

 

 

Abstract. Mathematical-chemical investigation of some alkenes was carried out within the scope of the quasi–ANB-matrices method. Three correlation equations of the structure-properties type were derived. Correlations are satisfactory.

Keywords: alkanes, quasi-ANB–matrix, correlation equation.

               

MATHEMATICAL-CHEMICAL INVESTIGATION OF CHAIN GROWTH IN THE REACTION OF METHANE HALOGENETATION

 

Chachava G.G. and  Gverdsiteli M.I.

 

National Food Agency

Iv. Javakhishvili Tbilisi State University

 

Abstract. The chain growth in the reaction of methane halogenation was studied within the scope of ANB – and quasi–ANB–matrices methods. Two correlation equations of the structure-properties type were derived and investigated. The correlations are satisfactory.

Keywords: chain growth, methane halogenation, correlation equation.

 

 

 

 

 

MATHEMATICAL-CHEMICAL INVESTIGATION OF ALKYNES  WITHIN

THE SCOPE OF THE QUASI-ANB–MATRICES  METHOD

 

Sidamonidze N.N.,  Koiava N.A. and  Gverdtsiteli M.I.

 

Iv. Javakhishvili Tbilisi State University

Tbilisi State Medical University

 

Abstract.    Mathematical-chemical investigation of some alkynes was carried out within the scope of the quasi-ANB-matrices method. Three  correlation equations of the structure-propertes type were derived. The correlations are satisfactory.

Keywords:   alkynes,   quasi-ANB-matrix,   correlation equations.

       

SUMMARY

SPECIFIC CONFORMATICAL STRUCTURE BIOCOMPLEXES OF CLOTRIMAZOLE AS A RESULT OF ENHANCEMENT OF CYTOTOXIC ACTIVITY

Chigogidze N.Sh., Tsivtsivadze T.I., Nadiradze I.Sh., Petriashvili Zh.D .,

Kldiashvili R.S and Japaridze R.J.

Scientific Center of Biologically Active Substances, Georgian Technical University

Coordinate compounds of bivalent copper with clotrimazole were synthesized, and their composition, structure and biological activity were studied. Preparation clotrimazole (bioligand) belongs to imidazole derivatives (heterocyclic compounds) which combine different kinds of biological activity: antimicrobial, antiprotozoal, antifungal etc. It is shown that, by the reaction of complex formation with 3d-metals, both mutual enhancement of these activities and the emergence of an essentially new anticancirogenic activity of a complex compound of copper with clotrimazole, better than that of cisplatin, are possible. Possible mechanisms of the anticancirogenic effect of such complexes are discussed. The concept of the role of the formation of the specific pentacoordinate structure of the complexes of Cu2+ with imidazole derivatives in the enhancement of cytotoxic activity of these preparations, we proposed, is confirmed.

Keywords: tumor, cell, inhibitor, chemotherapy, imidazole derivatives.

 

CELL DESTRUCTION IN TUMOR FORMATIONS

 

Kadagishvili L.G.

 

V. Chavchanidze Institute  man of Cybernetics, Georgian Technical University

Georgian Engineering Academy

 

Abstract. The paper deals with the structural analysis of tumor formations. Every element of the cell has its own function. Oxidation reactions proceed in mitochondria which supply the cell with energy. In the cell, this energy originates a quantum process that, together with chromosomes and the cell membrane, generates a spin field among nucleolui. Energy is primary as an irritator in mitotic cell division. If by any reason the number of chromosomes in the cell is less or more than in the parent cell, this will cause significant changes in the cell. In particular, the cell division could be accelerated. The cell division rate depends on the quantum process generated in the cell, which also determines the character of a tumor formation. The location of tumor is covered by a kind of film. The information is transmitted to all cells like in the case of DNA. This must make it easier to obtain the information about the existence of a tumor formation.

Keywords: tumor, cell, chromosomes, quantum process, spin energy.

 

SUMMARY

RED DESSERT WINE PREPARED BY INNOVATIVE TECHNOLOGY

Kekelidze I.A.

Institute of Viticulture and Oenology, Agricultural University of Georgia

The paper deals with the enological characteristics of red wine samples prepared from grape cultivar Saperavi: dessert type – with standard technology and with various technological techniques with the aim of enrichment with phenolic compounds; dry type - with standard technology. It is shown that red dessert wine prepared by innovative technology is much more advanced as the high-quality drink in comparison with the standard dessert and dry red wine samples.

Keywords: red dessert wine, red dry wine, enological characteristics.